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. 2016 Jul 9;7(34):54596–54615. doi: 10.18632/oncotarget.10519

Table 2. Relationship between cytoplasmic ING5 expression and clinicopathological parameters of lung cancers.

Clinicopathological features n Cytoplasmic ING5 expression
+ ++ +++ PR (%) P value
Sex 0.253
 Female 214 40 60 85 29 81.3
 Male 440 61 128 188 63 86.1
Age(years) 0.025
 < 65 363 43 109 153 58 88.1
 ≥ 65 291 58 79 120 34 80.0
Tumor size(cm) 0.104
 < 3 211 47 56 79 29 77.7
 ≥ 3 408 53 125 182 48 87.0
Histological classification < 0.001
 Squamous cell carcinoma 288 22 95 122 49 92.4
 Adenocarcinoma 317 55 82 142 38 82.6
 Large cell carcinoma 28 12 7 7 2 57.1
 Small cell carcinoma 21 12 4 2 3 42.8
Lymphatic invasion 0.044
 − 488 65 143 207 73 86.7
 + 159 34 43 65 17 78.6
Venous invasion 0.149
 − 114 68 9 24 13 40.4
 + 18 7 2 7 2 61.1
Lymph node metastasis 0.046
 − 395 76 107 160 52 84.9
 + 250 25 78 109 38 90.0
UICC staging 0.109
 I–II 506 69 146 223 68 88.9
 III–IV 144 31 42 49 22 78.4
ki-67 expression 0.370
 − 60 37 5 14 4 38.3
 + ~ +++ 70 38 6 16 10 45.7
CPP32 expression 0.005
 − 30 24 2 3 1 80.0
 + ~ +++ 101 51 9 28 13 49.5
p53 expression 0.134
 − 72 44 7 16 5 38.9
 + ~ +++ 60 31 4 15 10 48.3

Abbreviations, PR, positive rate; UICC, Union Internationale Contre le Cancer.