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. 2016 Jul 21;7(34):54733–54743. doi: 10.18632/oncotarget.10752

Figure 2. MALAT1 promotion of osteosarcoma cell growth in vitro.

Figure 2

(A) MALAT1 knockdown was achieved by si-MALAT1 and the inhibitory efficiency was verified by real-time PCR. (B and C) MTT assays revealed that knockdown of MALAT1 attenuated the growth of both Saos2 and MG63 cell lines up to three days, compared with si-NC group. (D and E) BrdU assays revealed that knockdown of MALAT1 markedly reduced DNA synthesis in both Saos2 and MG63 cell lines. Data are presented as mean ± SD of three independent experiments.