Table 4. The association between the single-nucleotide polymorphisms and BC risk in Genotype model (adjusted by age, BMI and menopause).
Genotype | Cases | Controls | OR (95% CI) | P |
---|---|---|---|---|
rs843645 | ||||
TT | 99 | 94 | 1.00 [Ref] | |
GT | 66 | 86 | 0.729 (0.475–1.117) | 0.147 |
GG | 18 | 15 | 1.139 (0.543–2.391) | 0.730 |
rs11125529 | ||||
CC | 133 | 123 | 1.00 [Ref] | |
AC | 45 | 68 | 0.612 (0.391–0.959) | 0.032 |
AA | 5 | 4 | 1.156 (0.304–4.404) | 0.832 |
rs12615793 | ||||
GG | 129 | 120 | 1.00 [Ref] | |
AG | 49 | 70 | 0.651 (0.419–1.013) | 0.057 |
AA | 5 | 4 | 1.163 (0.305–4.432) | 0.825 |
rs843711 | ||||
TT | 39 | 46 | 1.00 [Ref] | |
CT | 89 | 108 | 0.972 (0.583–1.620) | 0.913 |
CC | 55 | 41 | 1.582 (0.879–2.848) | 0.126 |
rs11896604 | ||||
CC | 128 | 114 | 1.00 [Ref] | |
GC | 49 | 76 | 0.574 (0.37–0.891) | 0.013 |
GG | 6 | 5 | 1.069 (0.318–3.596) | 0.915 |
rs843706 | ||||
AA | 39 | 45 | 1.00 [Ref] | |
CA | 89 | 111 | 0.925 (0.555–1.543) | 0.766 |
CC | 55 | 38 | 1.670 (0.921–3.030) | 0.092 |
OR: odd ratio; CI: confidence interval;
p value was calculated by Wald test. *p < 0.05 indicates statistical significance.