Table 5. Haplotype frequency and their association with BC risk in case and control subjects (adjusted by age, BMI and menopause).
| SNPs | Haplotype | Freq % | P1 | OR | 95% CI | P2 | ||
|---|---|---|---|---|---|---|---|---|
| case | control | |||||||
| rs843645|rs11125529|rs12615793|rs8437 11|rs11896604|rs843706 |
TAATGA | 0.150 | 0.192 | 0.126 | 0.745 | 0.501 | 1.108 | 0.146 |
| TCGTGA | 0.016 | 0.023 | 0.510 | 0.741 | 0.256 | 2.149 | 0.581 | |
| GCGTCA | 0.276 | 0.292 | 0.619 | 0.912 | 0.662 | 1.257 | 0.574 | |
| TCGCCC | 0.530 | 0.474 | 0.126 | 1.266 | 0.939 | 1.707 | 0.122 | |
*P-value < 0.05 indicates statistical significance.
P1- values were calculated from two-sided Chi-squared test.
P2 -values were calculated by unconditional logistic regression.
The reference standard for each haplotype is the other haplotype.