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. 2016 Jul 19;7(34):54998–55011. doi: 10.18632/oncotarget.10714

Figure 5. PIM-1 knockdown rescues proliferating PASMCs by inhibition of miR-328.

Figure 5

(A) Representative western blot of PIM-1 expression (up panel) and the quantification (down panel) in PASMCs infected with shPIM-1 lentivirus. (B and C) Effect of PIM-1 knockdown on the proliferation of PASMCs stimulated with PDGFBB. (D and E) Rescue experiments on EdU incorporation assay. PASMCs were transfected with inhibitor miR-328 and then infected with shPIM-1 lentivirus for 48 h, and the cell proliferation was measured. Results are shown as means ± SD of three independent experiments. *p < 0.05 compared to control without PDGFBB treatment (PDGFBB-).