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. 2016 Jul 26;7(34):55012–55025. doi: 10.18632/oncotarget.10839

Table 2. Pathways identified by MiRSEA with FDR < 0.01 in the gastric adenocarcinoma dataset.

Pathway Size of miRNAa NmiRES FDR Character
Leukocyte transendothelial migration 40 2.24 < 0.001 Down-regulated
Focal adhesion 79 2.04 < 0.001 Down-regulated
Selenoamino acids metabolism 10 2.03 < 0.001 Down-regulated
Fc gamma R-mediated phagocytosis 40 1.97 < 0.001 Down-regulated
Pathways in cancer 111 1.87 < 0.001 Down-regulated
VEGF signaling pathway 48 1.827 < 0.001 Down-regulated
Small cell lung cancer 73 1.79 < 0.001 Down-regulated
Regulation of actin cytoskeleton 59 1.77 < 0.001 Down-regulated
Colorectal cancer 70 1.68 < 0.001 Down-regulated
Notch signaling pathway 23 1.78 0.009 Down-regulated
Chemokine signaling pathway 59 1.78 0.009 Down-regulated
Cysteine and methionine metabolism 23 1.76 0.009 Down-regulated
Leishmania Infection 29 1.72 0.009 Down-regulated
MAPK signaling pathway 74 1.60 0.009 Down-regulated
Prostate cancer 86 1.55 0.009 Down-regulated
One carbon pool by folate 12 −1.72 0.014 Up-regulated
Amino sugar and nucleotide sugar metabolism 15 −1.53 0.055 Up-regulated
a

the number of miRNAs in the converted pathway.