Table 1. Correlation between HBxΔ31, Maspin, RhoGDIα and CAPZB expression and clinicopathological features in human HCCs.
Characteristics | Tumor HBxΔ31 expression | P value | Tumor Maspin expression | P value | Tumor RhoGDIα expression | P value | Tumor CAPZB expression | P value | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Negative (34) | Positive (68) | Negative (52) | Positive (50) | Negative (55) | Positive (47) | Negative (62) | Positive (40) | |||||
Age (yr) | 50.5 (7.9) | 51.4 (8.1) | 50.9 (8.1) | 50.1 (8.5) | 51.8 (8.2) | 50.5 (8.9) | 50.9 (8.4) | 52.1 (8.1) | ||||
Gender | ||||||||||||
Male | 25 | 51 | 0.421 | 45 | 39 | 0.642 | 39 | 37 | 0.198 | 40 | 36 | 0.559 |
Female | 10 | 16 | 12 | 6 | 16 | 10 | 18 | 8 | ||||
Serum AFP | ||||||||||||
<20ng/mL | 15 | 27 | 0.887 | 37 | 26 | 0.121 | 33 | 30 | 0.195 | 35 | 26 | 0.87 |
≥20ng/mL | 21 | 39 | 25 | 14 | 20 | 19 | 20 | 21 | ||||
Cirrhosis | ||||||||||||
Absent | 15 | 28 | 0.061 | 25 | 14 | 0.78 | 22 | 20 | 0.188 | 24 | 21 | 0.112 |
Present | 20 | 39 | 33 | 30 | 30 | 28 | 31 | 26 | ||||
Child-Pugh score | ||||||||||||
Class A | 27 | 35 | 0.316 | 41 | 35 | 0.12 | 40 | 36 | 0.552 | 35 | 30 | 0.305 |
Class B | 11 | 29 | 11 | 15 | 14 | 12 | 20 | 17 | ||||
Tumor number | ||||||||||||
Single | 25 | 37 | 0.306 | 38 | 36 | 0.632 | 35 | 36 | 0.145 | 40 | 32 | 0.411 |
Multiple | 14 | 26 | 13 | 15 | 14 | 17 | 11 | 19 | ||||
Tumor size | ||||||||||||
<5cm | 28 | 39 | 0.205 | 42 | 37 | 0.78 | 40 | 32 | O.558 | 44 | 30 | 0.553 |
≥5cm | 14 | 31 | 10 | 13 | 18 | 12 | 15 | 13 | ||||
Tumor encapsulation | ||||||||||||
Absent | 10 | 25 | 0.078 | 21 | 20 | 0.065 | 19 | 21 | 0.894 | 22 | 18 | 0.059 |
Present | 27 | 40 | 34 | 27 | 33 | 29 | 35 | 27 | ||||
Microvascular invasion | ||||||||||||
Absent | 23 | 38 | 0.052 | 40 | 28 | 0.001* | 32 | 19 | 0.042* | 30 | 21 | 0.762 |
Present | 12 | 29 | 22 | 12 | 20 | 29 | 25 | 26 | ||||
Tumor differentiation | ||||||||||||
I-II | 21 | 40 | 0.061 | 30 | 25 | 0.049* | 31 | 32 | 0.19 | 32 | 26 | 0.222 |
III-IV | 11 | 30 | 19 | 28 | 21 | 18 | 20 | 24 | ||||
Intrahepatic metastasis | ||||||||||||
Absent | 10 | 31 | 0.001* | 40 | 19 | <0.001* | 36 | 17 | 0.021* | 32 | 15 | 0.012* |
Present | 18 | 43 | 32 | 11 | 29 | 20 | 35 | 20 | ||||
TNM stage | ||||||||||||
I-II | 22 | 46 | 0.059 | 36 | 28 | 0.12 | 32 | 34 | 0.106 | 30 | 35 | 0.114 |
III-IV | 11 | 25 | 22 | 16 | 21 | 13 | 24 | 13 |
P<0.05