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. 2016 Jul 4;7(34):55110–55127. doi: 10.18632/oncotarget.10399

Table 1. Correlation between HBxΔ31, Maspin, RhoGDIα and CAPZB expression and clinicopathological features in human HCCs.

Characteristics Tumor HBxΔ31 expression P value Tumor Maspin expression P value Tumor RhoGDIα expression P value Tumor CAPZB expression P value
Negative (34) Positive (68) Negative (52) Positive (50) Negative (55) Positive (47) Negative (62) Positive (40)
Age (yr) 50.5 (7.9) 51.4 (8.1) 50.9 (8.1) 50.1 (8.5) 51.8 (8.2) 50.5 (8.9) 50.9 (8.4) 52.1 (8.1)
Gender
 Male 25 51 0.421 45 39 0.642 39 37 0.198 40 36 0.559
 Female 10 16 12 6 16 10 18 8
Serum AFP
 <20ng/mL 15 27 0.887 37 26 0.121 33 30 0.195 35 26 0.87
 ≥20ng/mL 21 39 25 14 20 19 20 21
Cirrhosis
 Absent 15 28 0.061 25 14 0.78 22 20 0.188 24 21 0.112
 Present 20 39 33 30 30 28 31 26
Child-Pugh score
 Class A 27 35 0.316 41 35 0.12 40 36 0.552 35 30 0.305
 Class B 11 29 11 15 14 12 20 17
Tumor number
 Single 25 37 0.306 38 36 0.632 35 36 0.145 40 32 0.411
 Multiple 14 26 13 15 14 17 11 19
Tumor size
 <5cm 28 39 0.205 42 37 0.78 40 32 O.558 44 30 0.553
 ≥5cm 14 31 10 13 18 12 15 13
Tumor encapsulation
 Absent 10 25 0.078 21 20 0.065 19 21 0.894 22 18 0.059
 Present 27 40 34 27 33 29 35 27
Microvascular invasion
 Absent 23 38 0.052 40 28 0.001* 32 19 0.042* 30 21 0.762
 Present 12 29 22 12 20 29 25 26
Tumor differentiation
 I-II 21 40 0.061 30 25 0.049* 31 32 0.19 32 26 0.222
 III-IV 11 30 19 28 21 18 20 24
Intrahepatic metastasis
 Absent 10 31 0.001* 40 19 <0.001* 36 17 0.021* 32 15 0.012*
 Present 18 43 32 11 29 20 35 20
TNM stage
 I-II 22 46 0.059 36 28 0.12 32 34 0.106 30 35 0.114
 III-IV 11 25 22 16 21 13 24 13
*

P<0.05