Table 1. Characteristics of breast cancer patients.
| Characteristic | Levels | Recurrence (n=28) | No recurrence (n=62) | P value* |
|---|---|---|---|---|
| Age, mean (SD) | 47.5 (11.5) | 50.4 (11.7) | 0.28 | |
| Race | White American | 11 | 39 | 0.057 |
| African American | 16 | 20 | ||
| Asian American | 1 | 3 | ||
| T stage | T1 | 10 | 30 | 0.065 |
| T2 | 9 | 20 | ||
| T3 | 2 | 11 | ||
| T4 | 4 | 1 | ||
| N stage | N0 | 8 | 34 | 0.10 |
| N1 | 14 | 23 | ||
| N2 | 2 | 4 | ||
| N3 | 2 | 1 | ||
| AJCC stage group | I | 6 | 19 | 0.23 |
| II | 9 | 29 | ||
| III | 9 | 14 | ||
| IV | 1 | 0 | ||
| Histology | Ductal | 24 | 44 | 0.38 |
| Lobular | 0 | 5 | ||
| Ductal & lobular | 2 | 6 | ||
| Others | 2 | 6 | ||
| Grade | G1 | 0 | 5 | 0.035 |
| G2 | 5 | 25 | ||
| G3 | 20 | 31 | ||
| Estrogen receptor (ER) | Negative | 18 | 29 | 0.17 |
| Positive | 10 | 33 | ||
| Progesterone receptor | Negative | 20 | 32 | 0.11 |
| (PR) | Positive | 8 | 30 | |
| HER2 | Negative | 21 | 58 | 0.031 |
| Positive | 7 | 4 | ||
| Triple negative | No | 15 | 35 | 0.82 |
| Yes | 13 | 27 | ||
| Mutation status | BRCA1 carrier | 2 | ||
| BRCA2 carrier | 1 | |||
| Type of recurrence | Locoregional | 8 | ||
| Distant metastasis | 20 | |||
| Site of distant metastasis | Bone | 8 | ||
| Distant lymph nodes | 8 | |||
| Lung | 7 | |||
| Brain | 3 | |||
| Liver | 3 | |||
| Pleura | 2 | |||
| Phase of the study | Discovery | 8 | 40 | |
| Validation | 20 | 22 |
*
t test or Fisher's exact test for continuous and categorical characteristics, respectively