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. 2016 Jul 25;7(34):55543–55554. doi: 10.18632/oncotarget.10837

Figure 6. TGF-β1 induces FASN in cisplatin-resistant lung cancer cells.

Figure 6

A, B. qPCR (A) and Western blot (B) analysis showing TGF-β1 and FASN mRNA (A) and protein (B) levels in A549CisR and H157CisR cells upon treatment with either vehicle or the TGF-β1 inhibitor SB525334 (SB) for 48 hours. C, D. qPCR (C) and Western blot (D) analysis showing FASN mRNA and protein levels in A549P/A549CisR and H157P/H157CisR cells after culturing with hrTGF-β1 (2 and 10 ng/ml) (24 hours of incubation for mRNA level study and 72 hours of incubation for protein analysis). *p<0.05, **p<0.01.