Table 3. Logistic regression analysis of INPP5D rs35349669 and AD.

SNP	Total samplea			APOE ε4 (+)b		APOEε4 (-)b
rs35349669	OR(95%CI)	P	P for APOE interaction	OR(95%CI)	P	OR(95%CI)	P
Dom	0.773 (0.543-1.099)	0.151	1.167	0.846 (0.407-1.758)	0.654	0.744 (0.495-1.117)	0.154
Add	0.763 (0.539-1.080)	0.127	0.689	0.846 (0.407-1.758)	0.654	0.733 (0.492-1.093)	0.128
Rec	-	-	-	-	-	-	-

APOE, apolipoprotein E; ApoEε4 (+), APOE ε4 allele carrier; ApoEε4 (−), APOE ε4 allele noncarrier; SNP, single nucleotide polymorphism; Dom, dominant; Rec, recessive; Add, additive model; OR, odd ratio; CI, confidence interval

^a, adjusted for age, gender, and APOE ε4 allele status;

^b, adjusted for age, gender.

^-, the recessive genetic model could not be analysed when minor allele homozygote counts <14.