Table 4. INPP5D genotype and allele frequencies in AD cases and controls stratified by sex.
| N | Genotypes, n (%) | P | Alleles, n (%) | P | ||||
|---|---|---|---|---|---|---|---|---|
| CC | TC | TT | C | T | ||||
| AD | 984 | 930 (94.5) | 54 (5.5) | 0(0) | 0.167 | 1914 (97.3) | 54 (2.7) | 0.094 |
| Controls | 1352 | 1256 (92.9) | 94 (7.0) | 2 (0.1) | 2606 (96.4) | 98 (3.6) | ||
| Male | 1014 | 934 (92.11) | 78 (7.69) | 2 (0.20) | 1946 (95.96) | 82 (4.04) | ||
| AD | 406 | 378 (93.10) | 28 (6.90) | 0 | 0.464a | 784 (40.29) | 28 (34.15) | 0.266 |
| Controls | 608 | 556 (91.45) | 50 (8.22) | 2 (0.33) | 1162 (59.71) | 54 (65.85) | ||
| Female | 1322 | 1252 (94.70) | 70 (5.30) | 0 | 2574 (97.35) | 70 (2.65) | ||
| AD | 578 | 552 (95.5) | 26 (4.50) | 0 | 0.268a | 1130 (43.90) | 26 (37.14) | 0.261 |
| Controls | 744 | 700 (94.10) | 44 (5.9) | 0 | 1444 (56.10) | 44 (62.86) | ||
a
Fisher's exact test was performed