Figure 1. Association between age and mutational frequency in glioblastoma multiforme.
(A) Association between age and mutational load: analysis of 592 genes. The mean number of mutations was 3.44 (SD 9.4) for elderly patients and 3.49 (SD 8.165) for the younger patients (P = ns). (B) Association between age and mutational load: analysis of a panel of cancer-specific genes (N = 59). The mean number of mutations was 0.88 (SD 1.09) in elderly patients and 1.39 (SD 1.611) in younger patients (P = 0.004).