Figure 6. Inhibited growth of MM tumors in vivo with uPAR knock down.
(A) The growth suppression in vivo upon uPAR knockdown in EM and SM cells in nude mice (n = 4 per group). uPAR and pAKT expression in xenograft tumors with (B) immunochemistry and (C) Western blot analyses. EM, epithelioid subtype mesothelioma; SM, sarcomatoid subtype mesothelioma (means ± SD; *P < 0.05, **P < 0.01).