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. 2016 Sep 8;7(43):69625–69637. doi: 10.18632/oncotarget.11904

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Copyright: © 2016 Kojima et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Mantle cell lymphoma (MCL) cells were treated for 72 hours with GSK2830371 (GSK) and Nutlin-3a (N3a), bortezomib (BTZ), or doxorubicin (DOX) either as individual agents or in combination, after which the annexin V-positive fractions were determined. The combination index (CI) values for the apoptotic effect were calculated in Z-138 cells for each combination.