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. 2016 Sep 10;7(43):69649–69665. doi: 10.18632/oncotarget.11935

Table 4. Interaction between CDCP1-IHC or -FISH status and N status in disease-free survival and distant disease-free survival.

Disease-free survival Distant disease-free survival
HR (95% CI) p 5-year survival HR (95% CI) p 5-year survival
IHC-N- 1.00 0.80 (0.55–0.92) 1.00 0.80 (0.55–0.92)
IHC+N- 0.85 (0.19–3.72) 0.828 0.85 (0.61–0.95) 0.40 (0.07–2.27) 0.414 0.89 (0.63–0.97)
IHC-N+ 1.21 (0.21–6.84) 0.829 0.74 (0.29–0.93) 0.56 (0.06–5.06) 0.946 0.89 (0.43–0.98)
IHC+N+ 5.25 (1.51–18.20) 0.009 0.30 (0.12–0.50) 3.32 (1.03–10.70) 0.044 0.31 (0.13–0.52)
FISH-N- 1.00 0.82 (0.64–0.91) 1.00 0.84 (0.66–0.93)
FISH+N- 0.76 (0.09–6.64) 0.800 0.86 (0.33–0.98) 0.69 (0.08–6.20) 0.744 0.86 (0.33–0.98)
FISH-N+ 2.03 (0.64–6.51) 0.231 0.61 (0.34–0.80) 1.87 (0.53–6.59) 0.332 0.65 (0.37–0.83)
FISH+N+ 8.89 (2.64–29.92) < 0.001 0.09 (0.01–0.33) 7.18 (2.09–24.65) 0.002 0.12 (0.01–0.40)

Adjusted hazard ratios (HRs) from a Cox multivariable model (with age, tumor size, Ki-67 levels, and DCIS as additional covariates); significance (p) of the HRs and estimated 5-year survival are listed.