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. 2016 Sep 13;7(43):69816–69828. doi: 10.18632/oncotarget.12002

Figure 2. Adherently cultured GSK126-responsive organoids remain sensitive to EZH2 inhibition.

Figure 2

(A) Western blot confirming reduction of H3K27me3 in adherent organoid cultures upon 14 days of GSK126 treatment. (B) Left panel: microscopy images of adherently cultured P7T and P19TA, treated with either 4 μM of GSK126 or DMSO for fourteen days. Right panel: bar plot showing the average fold expansion in number of cells after fourteen days of DMSO or GSK126 treatment. Error bars indicate standard deviation. Scale bar: 100 μm, same magnification applies to all images in (B).