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. 2016 Sep 13;7(43):69844–69856. doi: 10.18632/oncotarget.12004

Figure 1. HIF-1α protein expression is a prognostic marker.

Figure 1

(A and C) Percentage of patients with low epithelial and high stromal HIF-1α expression in complex atypical hyperplasia (CAH), endometrioid endometrial carcinoma (EEC) grade 1, 2 and 3 and non-endometrioid subtype (NEEC). Number of patients indicated above the bars. Total number of patients indicated under the graph. Given p-values are calculated between the indicated groups using Chi-squared test. (B and D) Kaplan-Meier curves depicting disease specific survival in endometrial cancer (EC) patients according to high or low HIF-1α epithelial (B) and stromal (D) protein expression. For each category: number of cases (number of disease specific deaths).