Figure 3. Hypoxia gene signature correlates to imaging and tissue biomarkers.
A pre-defined hypoxia gene signature [17] correlates to DCE-MRI parameter in 91 primary endometrial cancer (EC) lesions (A), FDG-PET/CT in 48 primary EC lesions (B–D) and expression of relevant genes (E–G) in 282 patients with complex atypical hyperplasia (CAH, n = 22) and primary endometrial cancer (EC, n = 260). rs = correlation coefficient.