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. 2016 Aug 24;7(43):69945–69960. doi: 10.18632/oncotarget.11566

Table 1. Inhibitory effects of Bisindolylmaleimide IX on a variety of kinases.

enzyme compounds IC50
Aurora A B-Raf IKKβ Jak2 SYK BCR-ABL ERK1 MEK1
Bis-IX (μM) >45 1.14±0.11 0.48±0.005 9.68±0.79 > 45 > 45 > 45 > 45
Stauprorine (nM) 13.71±2.71 3.37±0.17 1.54±0.12 0.76±0.04 1.16±0.08 N.D. N.D. N.D.
Imatinib (μg/ml) N.D. N.D. N.D. N.D. N.D. 0.023±0.003 N.D. N.D.

N.D. : not determined

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