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. 2016 Sep 20;7(43):70045–70057. doi: 10.18632/oncotarget.12145

Figure 4. PON3 inhibits cell proliferation and clonogenicity in HCC cells.

Figure 4

(A and B) Cell proliferation was determined by CCK-8 assay, and growth curves were generated by reading the absorbance value at different time points. Growth curves of (A) PON3 knockdown and (B) PON3 overexpression cells and their respective controls are shown. (C and D) Representative results of colony formation assays of (C) PON3 knockdown cells, (D) PON3 overexpression cells and their respective controls. *p < 0.05; **p < 0.01; ***p < 0.0001 compared with the respective controls. Significance was determined from three independent experiments and assessed by student's t-test. Data are shown as mean ± SD.