Table 3. Univariate and multivariate analyses of overall survival according to clinicopathological parameters and SPARC levels with 1000 bootstraping.

Characteristics	No		Uni–variant analysis			Multi–variant analysis
	Patients	Events	HR	95% CI	P–value	HR	95% CI	P–value	Bootstrapping 95% CI
Age (years)	137	71	1.011	0.988–1.034	0.368
Gender			1.124	0.635–1.988	0.689
Female	34	15
Male	103	56
Surgery D2			0.508	0.185–1.396	0.189	0.296	0.103–0.852	0.024	0.076–0.847
Yes	131	67
No	6	4
Location			0.750	0.516–1.089	0.130
Fundus & cardia	8	6
Body	55	31
Antrum & pylous	74	34
Differentiation			1.047	0.655–1.675	0.847
Well & moderate	62	33
Poor & mixed	75	38
Lauren type			1.627	0.998–2.650	0.051
Intestinal	59	25
Diffused	78	46
T stage			2.769	1.313–5.837	0.007	3.032	1.394–6.594	0.005	1.608–8.174
T1–T3	29	8
T4	108	63
N stage			3.917	1.692–9.067	0.001	3.866	1.664–8.982	0.002	1.865–10.979
N0	31	6
N1–N3	106	65
M stage			1.409	0.431–4.609	0.571
M0	133	68
M1	4	3
SPARC expression			1.798	1.080–2.995	0.024	1.835	1.093–3.083	0.022	1.179–3.401
Negative	53	21
Positive	84	50