Figure 1. PER1 is most efficiently knocked down in the PER1-shRNA-I group among five groups of SCC15 cells.

A. Levels of PER1 protein in the SCC15, Control-shRNA and PER1-shRNA-I-III groups. B. Levels of PER1 protein were significantly reduced in SCC15 cells transfected with PER1-shRNA-I. C. Expression of PER1 mRNA was significantly down-regulated in SCC15 cells transfected with PER1-shRNA-I. Data are presented as the mean ± SD. Significant differences between multiple groups were evaluated using ANOVA; differences between two groups were evaluated using the LSD test. *P<0.05 was considered statistically significant.