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. 2016 Sep 13;7(43):70462–70474. doi: 10.18632/oncotarget.11992

Figure 5. Runx1/2 and targeting miRNA molecular interactions in Prostate Cancer Signaling network.

Figure 5

Genes that interact with Runx1, Runx2, and selected Runx targeting miRNAs (Figures 3, 4) were identified using IPA (www.ingenuity.com) and mapped to the Prostate Cancer Signaling network. Orange genes interact with Runx1; Green genes interact with Runx2; Red genes interact with both Runx1 and Runx2. Blue boxes highlight PI3K/AKT/PTEN and control of cell growth as centers through which Runx1, Runx2, and Runx-targeting miRNAs function.