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. 2016 Sep 20;7(43):70589–70600. doi: 10.18632/oncotarget.12130

Table 3. Frequency and type of ZNRF3 mutations.

Cohort n Number of cancers mutated Total number of mutations Frameshift mutations Mis/nonsense (%A) (%B)
BRAF mutant /MSI 54 16 (29.6%) 18 13 (24.1%) 5 (9.3%)
BRAF mutant /MSS 33 5 (15.2%) 5 1 (3.0%) 4 (9.1%)
BRAF wild type /MSS 27 0 0 0 0

P value for number of mutations: Overall p=0.004; BRAF mutant/MSI vs BRAF mutant/MSS p=0.2; BRAF mutant/MSI vs BRAF wild type p=0.008; BRAF mutant/MSS vs BRAF wild type p=0.06