Skip to main content
. 2016 Sep 23;7(43):70685–70698. doi: 10.18632/oncotarget.12206

Table 2. Summary of the variants.

Family Location in APC (GRCh37/GRCh38) Insertion length (bp) Genomic variant RNA alteration Predicted protein alteration
FAP42 intron 6 (5:112126337/5:112790640) 127 c.646-1806T>G r.645_646ins646-1933_646-1807 p.Arg216*
FAP85 intron 11 (5:112158419/5:112822720) 83 c.1408+731C>T r.1408_1409ins1408+647_1408+729 p.Gly471Serfs*55
AFAP163 intron 11 (5:112158417/5:112822722) 83 c.1408+729A>G r.1408_1409ins1408+647_1408+729 p.Gly471Serfs*55

Note: An updated APC nomenclature based on 16 exons (NM_012583R138.4, ENST012583R10257430) was used for exon annotation.