Table 1. Demographics and clinical characteristics of enrolled patients.

Characteristics	All patients		Arm A		Arm B		p-value
	N = 146	%	N = 71	%	N = 75	%
Age
Median	51		52		50		0.78
Range	28–75		30–73		28–75
Histology
SCC	106	72.6	51	71.8	55	73.3	0.84
Non-SCC	40	27.4	20	28.2	20	26.7
FIGO stage
IA2	16	10.9	6	8.5	10	13.1	0.61
IB	69	47.2	36	50.7	33	44
IIA	43	29.6	19	26.8	24	32
MIIB	18	12.3	10	14	8	10.7
Differentiation
Well	14	9.6	4	5.6	10	13.3	0.21
Moderate	91	62.3	44	62	47	62.7
Poor	41	28.1	23	32.4	18	24
Largest diameter
Mean	2.9		2.8		3		0.54
Range	0.5–6.0		0.5–5.8		0.5–6.0
Number of positive pelvic nodes
0	27	18.5	16	22.5	11	14.7	0.29
1–2	76	52.1	36	50.7	40	53.3
3–4	24	16.4	13	18.3	11	14.7
> 4	19	13	6	8.5	13	17.3
Lymphovascular invasion
Negative	74	50.7	39	54.9	35	46.7	0.32
Positive	72	49.3	32	45.1	40	53.3
Stromal invasion depth
< 1/3	28	19.2	16	22.5	12	16	0.32
> 1/3	118	80.8	55	77.5	63	84
Positive parametrium
Yes	17	11.6	9	12.7	8	10.7	0.71
No	129	88.4	61	87.3	67	89.3
Positive surgical margin
Yes	6	4.1	4	5.6	2	2.7	0.37
No	140	95.9	67	94.3	73	97.3

Abbreviation: FIGO, International Federation of Gynecology and Obstetrics; SCC, squamous cell carcinoma; Non-SCC group consists of 20 adenosquamous cell carcinomas, 16 adenocarcinomas, and 4 mixed type.