Table 3. Results of multivariate analysis using the Cox proportional hazards model.
| Variance | P value | Hazard ratio | 95.0% Confidence interval |
|---|---|---|---|
| Age | |||
| ≤45years | 1 | ||
| >45years | <0.001 | 1.320 | 1.231-1.416 |
| Race | |||
| White | 1 | ||
| Black | <0.001 | 1.280 | 1.204-1.362 |
| Other | <0.001 | 0.797 | 0.719-0.882 |
| Grade | |||
| Well | 1 | ||
| Moderate | 0.131 | 1.097 | 0.973-1.237 |
| Poor | <0.001 | 1.440 | 1.278-1.622 |
| Stage T | |||
| T1a | 1 | ||
| T2 | 0.341 | 1.046 | 0.954-1.147 |
| T3 | 0.006 | 1.163 | 1.045-1.294 |
| T4 | <0.001 | 1.384 | 1.266-1.512 |
| Radiation | |||
| Done | 1 | ||
| None | 0.847 | 0.995 | 0.946-1.046 |
| HR | |||
| Positive | 1 | ||
| Negative | <0.001 | 1.714 | 1.616-1.817 |
| Surgery | |||
| No resection | 1 | ||
| R0 resection | <0.001 | 0.558 | 0.471-0.661 |
| Primary resection | <0.001 | 0.590 | 0.557-0.625 |
| Metastases resection | <0.001 | 0.782 | 0.693-0.883 |
| Metastatic site | |||
| Distant lymph node | 1 | ||
| Designated organsb | <0.001 | 1.838 | 1.622-2.083 |
| Other organs | <0.001 | 1.839 | 1.622-2.084 |
| Multiplec | <0.001 | 2.245 | 1.962-2.565 |
a
T0 merged into T1 when doing Cox multivariate analysis
b
Designated organs, metastasis in the following organs: adrenal (suprarenal) gland, bone, other than the adjacent rib, contralateral (opposite) breast, lung, ovary, satellite nodule(s) in skin other than the primary breast.
c
Multiple mean metastases in at least two of the above sites.