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LYRM03 inhibited the LPS-induced expression of inflammatory factors in alveolar macrophages. Alveolar macrophages were isolated from murine lung tissues. Cells were collected and incubated with or without LYRM03 (100 μmol/L) for 1 h, followed by treatments with LPS (100 ng/mL) for 0, 2, and 4 h. The expression levels of TNF-α (A), IL-6 (B), IL-1β (C), MIP-2 (D), iNOS (E), and COX-2 (F) were measured by quantitative PCR. The values represent the mean±SD. n= 4. *P<0.05, **P<0.01.
