Figure 5. Protein expression of oxidative stress biomarkers in brain infarct region by day 60 after AIS (n = 6).
A. Protein expression of NOX-1, * vs. other groups with different symbols (†, ‡, §, ¶), p < 0.0001. B. Protein expression of NOX-2, * vs. other groups with different symbols (†, ‡, §, ¶), p < 0.0001. C. Oxidized protein expression, * vs. other groups with different symbols (†, ‡, §, ¶), p < 0.0001. (Note: left and right lanes shown on the upper panel represent protein molecular weight marker and control oxidized molecular protein standard, respectively). M.W = molecular weight; DNP = 1-3 dinitrophenylhydrazone. All statistical analyses were performed by one-way ANOVA, followed by Bonferroni multiple comparison post hoc test. Symbols (*, †, ‡, §, ¶) indicate significance (at 0.05 level). SC = sham control; AIS = acute ischemic stroke; ADMSC = adipose-derived mesenchymal stem cell; Ex = exosome.