Table 1. Patient characteristics.
| Demographics | Controls (N=17) | IPF (N=45) | p value |
|---|---|---|---|
| Age (years) | 48.2 ± 3.2 | 65.4 ± 1.8 | <10−3 |
| Gender male female |
13 4 |
37 8 |
0.721 |
| Smoking status non smoker ex smoker smoker |
2 3 9 |
16 24 2 |
<10−3 |
| PY | 36.0 ± 5.7 | 39.1 ± 7.1 | 0.764 |
| Lung Function | |||
| FEV1% | 92.7 ± 6.0 | 73.7 ± 3.1 | 0.009 |
| FVC% | 94.0 ± 5.4 | 71.6 ± 3.3 | 0.003 |
| FEV1%/FVC% | 79.7 ± 2.0 | 79.5 ± 1.2 | 0.938 |
| TLC% | 101.6 ± 7.7 | 67.6 ± 2.5 | <10−3 |
| DLco% | 79.2 ± 5.5 | 43.4 ± 2.3 | <10−3 |
| KCO% | 103.6 ± 8.1 | 77.5 ± 3.2 | 0.014 |
| BAL cell count | |||
| Macrophages % | 69 ± 8 | 73 ± 3 | 0.83 |
| Lymphocytes % | 24.3 ± 7.6 | 14.1 ± 2.7 | 0.17 |
| Neutrophils % | 3.7 ± 1.4 | 6.8 ± 1 | 0.12 |
| Eosinophils % | 0.8 ± 0.4 | 3.2 ± 0.6 | 0.04 |
Values are the means ± SEM. PY=pack years for ex and current smokers; FEV1= Forced expiratory volume in 1 second; FVC= Forced Vital Capacity; TLC= Total Lung Capacity; DLco= Transfer factor of the Lung for Carbon Monoxide; KCO= transfer coefficient.