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. 2016 Oct 21;7(46):74592–74601. doi: 10.18632/oncotarget.12816

Figure 1. Impaired IL-6, TNF and IFN-γ production by PBMC of SS patients induced by TLR activation.

Figure 1

PBMC from SS patients (n = 10, closed circle) and healthy controls (HC, n = 13, open circle) were cultured in medium (unstimulated, UNS) or with TLR agonists (TLR2-TLR9) for 48 h. Supernatants were assessed for IL-6, TNF and IFN-γ secretion with a cytometric bead array. The results are shown as medians and interquartile ranges (IQRs).*p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001 compared with the HC group; #p ≤ 0.05, ##p ≤ 0.01, ###p≤ 0.001 compared with the unstimulated culture.