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. 2016 Oct 21;7(46):74592–74601. doi: 10.18632/oncotarget.12816

Figure 2. Altered IL-10 and IL-13 secretion by PBMC of SS patients induced by TLR agonists.

Figure 2

PBMC from SS patients (n = 10, closed circle) and healthy controls (HC, n = 13, open circle, open circle) were cultured with medium (unstimulated, UNS) or stimulated for 48 h with TLR agonists (TLR2-TLR9). Supernatants were assessed for IL-10 and IL-13 secretion with a cytometric bead array. Horizontal line shows the detection limit for IL-13. The results are shown as medians and IQRs.*p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001 compared with the HC group; #p ≤ 0.05, ##p ≤ 0.01, ###p ≤ 0.001 compared with the unstimulated culture.