Table 1. Overview of network processes identified using GeneGO pathway analysis based on GEP.
CEM/WT_BTZ vs CEM/WT Process –networks | P value | CEM/BTZ7 vs CEM/WT_BTZ Process –networks | P value |
---|---|---|---|
Protein folding_Response to unfolded proteins | 9,87E-11 | Protein folding_Response to unfolded proteins | 6,19E-11 |
Protein folding_Folding in normal condition | 4,06E-07 | Apoptosis_Endoplasmic reticulum stress pathway | 1,17E-05 |
Apoptosis_Endoplasmic reticulum stress pathway | 3,34E-05 | Protein folding_Folding in normal condition | 2,42E-05 |
Apoptosis_Apoptotic mitochondria | 1,27E-03 | Apoptosis_Apoptotic mitochondria | 2,60E-04 |
Protein folding_Protein folding nucleus | 3,20E-03 | Reproduction_Male sex differentiation | 7,11E-04 |
Proteolysis_Ubiquitin-proteasomal proteolysis | 8,27E-03 | Immune response_Th17-derived cytokines | 1,12E-03 |
Inflammation_IL-6 signaling | 8,34E-03 | Reproduction_FSH-beta signaling pathway | 1,21E-03 |
Inflammation_Neutrophil activation | 9,02E-03 | Protein folding_Protein folding nucleus | 2,58E-03 |
Cytoskeleton_Intermediate filaments | 1,05E-02 | Inflammation_IL-6 signaling | 3,43E-03 |
Protein folding_ER and cytoplasm | 1,18E-02 | Reproduction_Spermatogenesis, motility and copulation | 4,45E-03 |
Corresponding P-values are given for the identified pathways. Pathways analysis was performed using GeneGO on significant altered genes (P < 0.05) and with a fold change > Log2.