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. 2016 Aug 17;7(46):74779–74796. doi: 10.18632/oncotarget.11340

Table 1. Overview of network processes identified using GeneGO pathway analysis based on GEP.

CEM/WT_BTZ vs CEM/WT Process –networks P value CEM/BTZ7 vs CEM/WT_BTZ Process –networks P value
Protein folding_Response to unfolded proteins 9,87E-11 Protein folding_Response to unfolded proteins 6,19E-11
Protein folding_Folding in normal condition 4,06E-07 Apoptosis_Endoplasmic reticulum stress pathway 1,17E-05
Apoptosis_Endoplasmic reticulum stress pathway 3,34E-05 Protein folding_Folding in normal condition 2,42E-05
Apoptosis_Apoptotic mitochondria 1,27E-03 Apoptosis_Apoptotic mitochondria 2,60E-04
Protein folding_Protein folding nucleus 3,20E-03 Reproduction_Male sex differentiation 7,11E-04
Proteolysis_Ubiquitin-proteasomal proteolysis 8,27E-03 Immune response_Th17-derived cytokines 1,12E-03
Inflammation_IL-6 signaling 8,34E-03 Reproduction_FSH-beta signaling pathway 1,21E-03
Inflammation_Neutrophil activation 9,02E-03 Protein folding_Protein folding nucleus 2,58E-03
Cytoskeleton_Intermediate filaments 1,05E-02 Inflammation_IL-6 signaling 3,43E-03
Protein folding_ER and cytoplasm 1,18E-02 Reproduction_Spermatogenesis, motility and copulation 4,45E-03

Corresponding P-values are given for the identified pathways. Pathways analysis was performed using GeneGO on significant altered genes (P < 0.05) and with a fold change > Log2.