Table 2. Overview of process-networks and gene ontology processes based on miRNA analysis.
Process -networks | P-value | GO-Processes | P-value |
---|---|---|---|
Proteolysis_Ubiquitin-proteasomal proteolysis | 2,95E-03 | Apoptotic process | 1,35E-07 |
Protein folding_Protein folding nucleus | 6,19E-03 | Programmed cell death | 2,23E-07 |
Cell adhesion_Leucocyte chemotaxis | 1,51E-02 | Cellular response to stress | 2,63E-07 |
Cytoskeleton_Regulation of cytoskeleton rearrangement | 1,64E-02 | Regulation of molecular function | 1,21E-06 |
Cell adhesion_Synaptic contact | 1,71E-02 | Cell death | 1,48E-06 |
Cell adhesion_Cell junctions | 1,84E-02 | Cellular response to oxidative stress | 1,55E-06 |
Cytoskeleton_Intermediate filaments | 2,89E-02 | Death | 1,68E-06 |
Cytoskeleton_Actin filaments | 3,06E-02 | Cellular protein metabolic process | 1,73E-06 |
Apoptosis_Apoptotic nucleus | 3,99E-02 | Cellular protein modification process | 2,47E-06 |
Reproduction_Progesterone signaling | 4,36E-02 | Protein modification process | 2,47E-06 |
Corresponding P-values are given for the identified pathways. Pathways analysis was performed using GeneGO on targets genes of the top10 miRNA's of which expression is correlating with gene expression.