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. 2016 Aug 17;7(46):74779–74796. doi: 10.18632/oncotarget.11340

Table 2. Overview of process-networks and gene ontology processes based on miRNA analysis.

Process -networks P-value GO-Processes P-value
Proteolysis_Ubiquitin-proteasomal proteolysis 2,95E-03 Apoptotic process 1,35E-07
Protein folding_Protein folding nucleus 6,19E-03 Programmed cell death 2,23E-07
Cell adhesion_Leucocyte chemotaxis 1,51E-02 Cellular response to stress 2,63E-07
Cytoskeleton_Regulation of cytoskeleton rearrangement 1,64E-02 Regulation of molecular function 1,21E-06
Cell adhesion_Synaptic contact 1,71E-02 Cell death 1,48E-06
Cell adhesion_Cell junctions 1,84E-02 Cellular response to oxidative stress 1,55E-06
Cytoskeleton_Intermediate filaments 2,89E-02 Death 1,68E-06
Cytoskeleton_Actin filaments 3,06E-02 Cellular protein metabolic process 1,73E-06
Apoptosis_Apoptotic nucleus 3,99E-02 Cellular protein modification process 2,47E-06
Reproduction_Progesterone signaling 4,36E-02 Protein modification process 2,47E-06

Corresponding P-values are given for the identified pathways. Pathways analysis was performed using GeneGO on targets genes of the top10 miRNA's of which expression is correlating with gene expression.