Table 3. Results of univariate and multivariate analyses.
| variable | Overall Survival | In-Field Failure-Free Survival | ||
|---|---|---|---|---|
| Log-rank | Cox model (HR) | Log-rank | Cox model (HR) | |
| FIGO III-IV | 0.959 | -- | 0.552 | -- |
| Tumor > 5 cm | 0.010 | 0.512 | 0.002 | 0.078 |
| Pelvic LN | 0.151 | -- | 0.099 | 0.288 |
| HR-CTV > 25 cc | 0.017 | 0.030 (2.86) | 0.002 | 0.008 (3.73) |
| Neutrophiliaa | 0.004 | 0.232 | 0.000 | 0.002 (4.50) |
| Leucocytosisa | 0.199 | 0.962 | 0.003 | 0.047 (2.54) |
| Anemia | 0.011 | 0.026 (3.05) | 0.065 | 0.233 |
| Variable | Local Failure-Free Survival | Distant Failure-Free Survival | ||
|---|---|---|---|---|
| Log-rank | Cox model (HR) | Log-rank | Cox model (HR) | |
| FIGO III-IV | 0.669 | -- | 0.433 | -- |
| Tumor > 5 cm | 0.003 | 0.383 | 0.013 | 0.005 (3.48) |
| Pelvic LN | 0.914 | -- | 0.047 | 0.028 (2.42) |
| HR-CTV > 25 cc | 0.003 | 0.026 (3.1) | 0.075 | 0.505 |
| Neutrophiliaa | 0.000 | 0.018 (3.1) | 0.590 | -- |
| Leucocytosisa | 0.002 | 0.287 | 0.564 | -- |
| Anemia | 0.036 | 0.177 | 0.020 | 0.324 |
Variables significant with a p value < 0.1 in univariate analysis were used for multivariate model (significant factors in multivariate analysis in bold).
FIGO: International Federation of Gynecology Obstetrics; HR: hazard ratio (given only if p < 0.05); HR CTV: high risk clinical target volume; LN: lymph nodes.
a
Neutrophilia and leucocytosis were not tested in the same model, as neutrophils are subpopulation of leucocytes.