Table 6. Cox model analysis for the correlation between the infiltrating density of CD68+ macrophages in tumor nest and hazard ratio (n = 138).
Clinical parameters | Univariate | Multivariate | ||||
---|---|---|---|---|---|---|
HR | 95% CI | P-value | HR | 95% CI | P-value | |
Gender | ||||||
Male/Female | 0.982 | 0.682−1.536 | 0.937 | 0.912 | 0.574−1.449 | 0.697 |
Age (years) | ||||||
≥ 60/< 60 | 0.930 | 0.627−1.378 | 0.717 | 0.842 | 0.559−1.269 | 0.412 |
Tumor size (cm) | ||||||
≥ 3.5/< 3.5 | 1.417 | 0.941−2.132 | 0.095 | 1.466 | 0.944−2.277 | 0.089 |
TNM Stage | ||||||
SIII/SII | 1.310 | 0.850−2.019 | 0.220 | 1.170 | 0.744−1.839 | 0.497 |
Treatment | ||||||
Chemotherapy/None | 1.132 | 0.610−2.098 | 0.695 | 0.935 | 0.491−1.780 | 0.837 |
Radiotherapy/ None | 0.651 | 0.398−1.064 | 0.087 | 0.599 | 0.363−0.987 | 0.044 |
Both/None | 0.658 | 0.091−4.743 | 0.678 | 0.823 | 0.106−6.380 | 0.852 |
CD68+ macrophages in tumor nest | ||||||
High/Low | 1.541 | 1.038−2.289 | 0.032 | 1.488 | 0.996−2.221 | 0.052 |
Values in bold signify P < 0.05.