Skip to main content
. 2016 Sep 6;7(46):75000–75012. doi: 10.18632/oncotarget.11852

Figure 2. nc886 KD activates PKR, which impairs cell proliferation.

Figure 2

A. Northern hybridization of nc886 and 5S rRNA as a loading control (top panel) and cell proliferation (MTS) assays (bottom panel) after nc886 KD. “anti-nc886” (an anti-oligo targeting nc886) and “anti-control” (targeting a paralog ncRNA vtRNA1-1 but not nc886) were transfected into indicated cells at 100 nM for 48 hrs. B. Western blot of indicated proteins after nc886 KD in panel A. Molecular sizes in kilodalton (kD) from the size marker are indicated on the right. C. Summary of nc886 KD data from panel A-B and expected cellular outcomes upon nc886 KO.