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. 2016 Oct 12;7(46):75038–75051. doi: 10.18632/oncotarget.12602

Figure 5. β-catenin is the direct target of miR-885-5p.

Figure 5

(A), Alignment of miR-885-5p with CTNNB1 at the 3′-UTR. (B), Effect of miR-885-5p on luciferase activity of Luc-CTNNB1-UTR and Luc-CTNNB1-UTR-mut. (C), Real-time qRT-PCR indicating the reduced levels of CTNNB1 when compared with the negative controls (NC) in the HCCLM3 and SK-Hep-1 HCC cell lines. (D), Western blots indicated reduced levels of β-catenin in miR-885-5p mimics or miR-NC transfected HCCLM3 and SK-Hep-1 cells. Levels of β-actin are shown as an internal control. *P < 0.05.