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. 2016 Sep 17;7(46):75185–75196. doi: 10.18632/oncotarget.12092

Figure 7. MiR-424-5p promoted tumor growth of GC cells in nude mice.

Figure 7

A. and B. Tumors were obtained from nude mice injected subcutaneously with cells transfected with miR-424-5p inhibitor and miR-424-5p mimics. C. and D. growth curve of tumor volumes. E. The average tumor weight of nude mice(*P<0.05). F. The expression levels of miR-424-5p in samples collected from nude mice. G. The protein expression levels of TGF-β, Smad3, c-Myc, CDK2, CDK4 and CDK6 in samples collected from nude mice were measured by western blotting. H. The protein expression levels of TGF-β, Smad3, c-Myc, CDK2, CDK4 and CDK6 in GC cells were measured by western blotting. I. The protein expression levels of TGF-β, Smad3, c-Myc, CDK2, CDK4 and CDK6 in MGC803 cells treated with LY364947 were measured by western blotting.