Table 1. Expression of miRNA-424-5p expression and Smad3 in human gastric cancer according to patients' clinicopathological characteristics.
Characteristics | Number (%) | miR-424-5p expression | P-value | Smad3 expression | P-value | ||
---|---|---|---|---|---|---|---|
High group | Low group | High group | Low group | ||||
Age(years) | |||||||
<60 | 18 | 7 | 11 | 0.380 | 10 | 8 | 0.425 |
≥60 | 45 | 23 | 22 | 20 | 25 | ||
Gender | |||||||
Male | 29 | 16 | 13 | 0.268 | 14 | 15 | 0.023 |
Female | 34 | 14 | 20 | 16 | 18 | ||
Size(cm) | |||||||
<3 | 30 | 9 | 21 | 0.008* | 20 | 10 | 0.004* |
≥3 | 33 | 21 | 12 | 10 | 23 | ||
Histology grade | |||||||
Well-moderately | 19 | 11 | 8 | 0.283 | 10 | 9 | 0.601 |
Poorly-signet | 44 | 19 | 25 | 20 | 24 | ||
stage | |||||||
I/II | 22 | 9 | 13 | 0.435 | 8 | 14 | 0.190 |
III/IV | 41 | 21 | 20 | 22 | 19 | ||
T grade | |||||||
T1+T2 | 20 | 8 | 12 | 0.058 | 7 | 13 | 0.171 |
T3+T4 | 43 | 22 | 21 | 23 | 20 | ||
Lymph node metastasis | |||||||
Present (N1-N3) | 40 | 22 | 18 | 0.122 | 16 | 24 | 0.110 |
Absent(N0) | 23 | 8 | 15 | 14 | 9 |
p<0.05 Statistically significant difference