Table 2. Association between rs589247 and ischemic stroke risk under multiple genetic models.
| SNP | Models | Genotype | Genotype frequency | OR (95%CI) | Pa | Pb | |
|---|---|---|---|---|---|---|---|
| Control | Case | ||||||
| rs589247 | Genotype | CC | 177 | 142 | 1.000 | ||
| TC | 228 | 244 | 1.33 (1.00-1.77) | 0.048* | 1 | ||
| TT | 98 | 102 | 1.30 (0.91-1.85) | 0.150 | 1 | ||
| Dominant | TT+TC | 326 | 346 | 1.32 (1.01-1.73) | 0.040* | 1 | |
| CC | 177 | 142 | 1.000 | ||||
| Recessive | TT | 98 | 102 | 1.09 (0.80-1.49) | 0.578 | 1 | |
| TC+CC | 405 | 386 | 1.000 | ||||
| Additive | - | - | - | 1.16 (0.97-1.38) | 0.098 | 1 | |
SNPs, single-nucleotide polymorphisms; OR, odds ratio; 95%CI, 95% confidence interval.
a
P values were calculated from unconditional logistic regression analysis.
b
P values were adjusted by Bonferroni correction.
*
P≤0.05 indicates statistical significance.