Table 1. Correlation of the average integrated density of FMRP⁺ cells with clinicopathological status in 74 patients with astrocytoma.

FMRP+ IOD	≤ 30 (n=32)	> 30 (n=42)	P value
Sex
Male	15	21	0.790
Female	17	21
Age
≤37	19	20	0.316
>37	13	22
Tumor size (cm3)a
≤30	20	16	0.037
>30	12	26
Pathological gradeb
II	22	19	0.044
III-IV	10	23
Ki-67c
≤5%	22	14	0.003
>5%	10	28

^aTumor size identified by magnetic resonance imaging before surgery and calculated with formula V=L×W×H/2 cm³ (V, volume; L, length; W, width; H, height).

^bGrading of the 74 cases of astrocytoma.

^cKi67 expression in astrocytoma tissue determined using immunohistochemistry.