. 2016 Sep 26;7(46):75457–75467. doi: 10.18632/oncotarget.12255

Table 4. Stratified analyses between rs12922061, rs2290203, rs2981578, and rs10474352 and breast cancer risk by ER status, HR status and subtype.

Characteristics	rs12922061		P^b	rs2290203		P^b	rs2981578		P^b	rs10474352		P^b
Characteristics	OR(95%CI)	P^a	P^b	OR(95%CI)	P^a	P^b	OR(95%CI)	P^a	P^b	OR(95%CI)	P^a	P^b
ER status			0.113			0.395			0.874			0.165
Positive	1.283 (1.114, 1.478)	0.001		1.217 (1.069, 1.384)	0.003		0.922 (0.871, 0.977)	0.006		0.947 (0.833, 1.075)	0.399
Negative	1.067 (0.889, 1.281)	0.485		1.111 (0.940, 1.314)	0.216		0.909 (0.770, 1.074)	0.262		0.818 (0.693, 0.965)	0.017
HR status			0.087			0.300			0.244			0.095
Positive	1.283 (1.116, 1.475)	4.7*10⁻⁴		1.221 (1.075, 1.387)	0.002		0.822 (0.723, 0.936)	0.003		0.952 (0.839, 1.079)	0.439
Negative	1.048 (0.866, 1.267)	0.630		1.091 (0.917, 1.297)	0.325		0.937 (0.790, 1.113)	0.460		0.796 (0.670, 0.946)	0.010
Subtype			0.031			0.276			0.293			0.555
Luminal	1.294 (1.113, 1.504)	0.001		1.174 (1.023, 1.348)	0.022		0.837 (0.729, 0.961)	0.012		0.936 (0.817, 1.071)	0.336
HER-2 overexpression	1.285 (1.058, 1.560)	0.011		1.385 (0.152, 1.664)	0.001		0.819 (0.681, 0.985)	0.034		0.886 (0.740, 1.061)	0.189
Basal-like	0.918 (0.717, 1.177)	0.501		0.976 (0.783, 1.216)	0.828		1.023 (0.823, 1.272)	0.837		0.815 (0.656, 1.014)	0.066

Adjusted for age, age at menarche and family history of breast cancer.

P for heterogeneity. P≤0.000446.