. 2016 Sep 26;7(46):75457–75467. doi: 10.18632/oncotarget.12255

Table 5. Stratified analyses between rs10816625, rs2296067, rs9693444, and rs4951011 and breast cancer risk.

Characteristics	rs10816625		P^b	P^c	rs2296067		P^b	P^c	rs9693444		P^b	P^c	rs4951011		P^b	P^c
Characteristics	OR(95%CI)	P^a	P^b	P^c	OR(95%CI)	P^a	P^b	P^c	OR(95%CI)	P^a	P^b	P^c	OR(95%CI)	P^a	P^b	P^c
Age (year)			0.099	0.125			0.686	0.704			0.911	0.905			0.285	0.259
≤40	0.960 (0.775, 1.188)	0.707			0.930 (0.747, 1.158)	0.517			1.024 (0.813, 1.291)	0.839			1.139 (0.911, 1.424)	0.254
>40	1.182 (1.029, 1.358)	0.018			0.981 (0.853, 1.127)	0.785			1.008 (0.869, 1.168)	0.919			0.979 (0.847, 1.132)	0.777
BMI			0.149	0.122			0.618	0.604			0.240	0.185			0.318	0.330
≤24	1.052 (0.915, 1.209)	0.492			0.990 (0.859, 1.140)	0.887			0.956 (0.824, 1.109)	0.551			1.066 (0.922, 1.233)	0.389
>24	1.282 (1.035, 1.587)	0.023			0.928 (0.750, 1.149)	0.493			1.136 (0.903, 1.431)	0.277			0.933 (0.746, 1.166)	0.540
Education level			0.450	0.425			0.981	0.960			0.811	0.830			0.283	0.296
Uneducated or primary school	1.194 (1.008, 1.414)	0.040			0.981 (0.828, 1.162)	0.822			1.043 (0.873, 1.245)	0.645			0.960 (0.806, 1.142)	0.641
High school or more	1.086 (0.910, 1.296)	0.360			0.984 (0.822, 1.177)	0.857			1.010 (0.833, 1.225)	0.916			1.106 (0.918, 1.332)	0.288
Age at menarche (year)			0.918	0.843			0.107	0.241			0.643	0.187			0.687	0.505
≤16	1.118 (0.984, 1.271)	0.088			0.924 (0.811, 1.053)	0.234			1.027 (0.893, 1.181)	0.709			1.048 (0.914, 1.201)	0.501
>16	1.100 (0.832, 1.455)	0.504			1.222 (0.927, 1.611)	0.154			0.954 (0.719, 1.265)	0.743			0.984 (0.746, 1.299)	0.910
Menopausal status			0.779	0.685			0.363	0.343			0.619	0.592			0.246	0.249
Premenopausal	1.094 (0.947, 1.264)	0.221			1.005 (0.869, 1.162)	0.946			1.033 (0.887, 1.204)	0.675			1.083 (0.931, 1.261)	0.300
Postmenopausal	1.134 (0.927, 1.387)	0.220			0.896 (0.731, 1.098)	0.290			0.966 (0.777, 1.200)	0.752			0.931 (0.755, 1.148)	0.506
Age at menopause (year)(postmenopausal women only)			0.999	0.865			0.762	0.774			0.818	0.870			0.930	0.926
<50	1.116 (0.781, 1.593)	0.547			0.985 (0.689, 1.407)	0.933			1.029 (0.712, 1.487)	0.879			0.944 (0.670, 1.330)	0.742
≥50	1.116 (0.886, 1.405)	0.352			0.920 (0.726, 1.167)	0.493			0.975 (0.758, 1.256)	0.847			0.926 (0.723, 1.186)	0.543
Years of menstruation (year)			0.793	0.751			0.121	0.109			0.203	0.196			0.335	0.335
<30	1.128 (0.947, 1.345)	0.178			1.070 (0.898, 1.274)	0.448			1.111 (0.922, 1.339)	0.267			1.095 (0.913, 1.314)	0.328
≥30	1.093 (0.936, 1.276)	0.263			0.884 (0.754, 1.036)	0.129			0.941 (0.795, 1.112)	0.475			0.969 (0.823, 1.141)	0.704
Age at first live birth (year)			0.096	0.017			0.047	0.164			0.818	0.620			0.400	0.846
≤25	1.199 (1.027, 1.400)	0.021			1.050 (0.900, 1.226)	0.532			1.007 (0.855, 1.186)	0.930			0.965 (0.823, 1.130)	0.656
>25	0.976 (0.809, 1.179)	0.801			0.818 (0.674, 0.994)	0.043			1.039 (0.845, 1.278)	0.718			1.081 (0.881, 1.326)	0.458
Parity			0.737	0.669			0.391	0.409			1.000	0.986			0.259	0.281
0-1	1.089 (0.922, 1.287)	0.313			0.924 (0.781, 1.093)	0.358			1.009 (0.843, 1.208)	0.924			1.119 (0.936, 1.337)	0.218
≥2	1.134 (0.961, 1.339)	0.137			1.026 (0.867, 1.213)	0.769			1.009 (0.846, 1.203)	0.919			0.969 (0.817, 1.149)	0.717
Breast feeding period (month)			0.903	0.827			0.347	0.400			0.060	0.032			0.562	0.624
<6	1.129 (0.852, 1.496)	0.397			0.856 (0.650, 1.126)	0.266			1.340 (1.006, 1.784)	0.046			1.112 (0.835, 1.482)	0.468
≥6	1.107 (0.973, 1.259)	0.122			0.986 (0.864, 1.124)	0.831			0.946 (0.823, 1.088)	0.437			1.008 (0.880, 1.154)	0.911
Family history of breast cancer			0.503	0.373			0.156	0.252			0.931	0.927			0.341	0.370
No	1.105 (0.983, 1.243)	0.940			0.976 (0.867, 1.099)	0.686			1.011 (0.892, 1.146)	0.865			1.033 (0.914, 1.168)	0.607
Yes	1.743 (0.689, 4.414)	0.241			0.556 (0.226, 1.364)	0.199			1.061 (0.422, 2.669)	0.899			0.703 (0.302, 1.637)	0.414

Adjusted for age, age at menarche and family history of breast cancer.

P for heterogeneity.

P for interaction. P≤0.000446.