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. 2016 Sep 30;7(46):75685–75697. doi: 10.18632/oncotarget.12353

Figure 2. Peptidoglycan helped to sustain the structure and function of the irradiated intestine.

Figure 2

A. A representative image of stools in the colon. B. Feces discharged from the bowels were counted at 1.25, 3.5, and 9 days after IR (n=3 per group). C. Body weights after radiotherapy were recorded every other day in each group for a total of 20 days (n=6 per group). D. Representative images of the pathologic and morphologic changes of the small intestinal villi in each group at 1.25, 3.5, and 9 days after IR using H&E staining (200× magnification). E. Villi height of each group (n=3) were measured and compared at 1.25, 3.5, and 9 days after IR. F. Number of intestinal crypts along the jejunum circumference (10 circuits in total) in each group at 1.25, 3.5, and 9 days after IR was counted. Data are shown as the mean of 10 circuits±standard deviation. Asterisk indicates p<0.05. G. immunohistochemistry of mouse intestinal tissue 1.25 days after 15 Gy IR. Arrows indicate the mTOR positive crypts (400×).