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. 2016 Oct 3;7(46):75810–75826. doi: 10.18632/oncotarget.12416

Figure 6. Differential amino acid conservation.

Figure 6

Differential position conservation between the DIRP dataset sequences and the general MSA (y-axis). Residues used as template correspond to the human HRas amino acid sequence (x-axis). A positive value in the difference of conservation indicates a position with higher level of conservation in the DIRP dataset than in the background dataset and a negative value indicates a position with a higher variability. Horizontal dark lines correspond to thresholds associated to p-values < 0.01.