Table 3. Ranked list of the DIRP specific positions based on their level of implication in Ras binding sites.
| Position | Number of matches | Complexes |
|---|---|---|
| I36 | 14 | 1NVU, 1XD2, 1LFD, 1WQ1, 2UZI, 2VHS, 3DDC, 1H8E, 3KUC, 1K8R, 1C1Y, 2C5L, 4DXA, 1UAD |
| Y64 | 9 | 1NVU, 1XD2, 1BKD, 1LFD, 3CF6, 1WQ1, ZUZI, 2VHS, 3DDC |
| D33 | 8 | 1LFD, 1NVU, 2UZI, 2VH5, 1HE8, 1XD2, 1WQ1, 3KUC |
| P34 | 8 | 1LFD, 1NVU, 2UZI, 2VH5, 1XD2, 1WQ1, 1BKD, 3CF6 |
| Y32 | 5 | 1NVU, 1BKD, 1LFD, 3CF6, 1WQ1 |
| A66 | 5 | 1NVU, 1XD2, 1BKD, 1LFD, 3CF6 |
| Y71 | 5 | 1NVU, 1XD2, 1BKD, 3CF6, 1ZC3 |
| D54 | 4 | 1NVU, 1BKD, 3CF6, 1K8R |
| G60 | 4 | 1NVU, 1BKD, 3CF6, 1WQ1 |
| T20 | 3 | 1NVU, 3CF6, 2A9K |
| A59 | 3 | 1NVU, 1BKD, 3CF6 |
| Q22 | 3 | 1NVU, 1XD2, 2A9K |
| G12 | 2 | 1LFD, 1WQ1 |
| V103 | 1 | 2A9K |
| I139 | 1 | 2BOV |
| T35 | 0 | Between interacting positions 34 & 36 in several complexes |
| R68 | 0 | Between interacting positions 67 & 69 in several complexes |
| T58 | 0 | Between interacting positions 57 & 59 in some complexes |
| F28 | 0 | Between interacting positions 27 & 29 in some complexes |
| G77 | 0 | |
| E153 | 0 | |
| C186 | 0 |
First column shows the amino acid position according to HRas sequence. Second column indicates the number of 3D complexes binding sites in which the position is directly involved. Third column contains PDB Id codes for the complexes that are related to each position or annotation of indirect relationships to binding sites.