Table 4. DIRP specific positions clustered in Ras functional regions.
Functional Regions | Positions | Ratio |
---|---|---|
Switch I (Effectors binding site) | Y32, D33, P34, T35, I36 | 23% |
Switch II | G60, Y64, A66, R68, Y71 | 23% |
C-terminal hyper variable region | C186 | 5% |
Nucleotide (GDP/GTP) binding site | G12, F28, T35, T58, A59, G60 | 27% |
Innert regions | T20, Q22, D54, G77, V103, I139, E153 | 32% |
First column lists the different functional region in Ras proteins. Second column indicates the DIRP amino acid position according to HRas sequence. Third column shows the percentage (Ratio) of DIRP specific positions in each functional region.