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Tumors from xenograft-transplanted nude mice 32 days after subcutaneous injection of SOX17-overexpressing, silenced or control HEC-1B cells A. Weights of xenografts 32 days after cell injection (*P<0.05) B. In vivo tumor growth curves for HEC-1B cells C. Paraffin-embedded sections obtained from xenografts D. IHC staining shows increased MAML3, β-catenin, CyclinD1, c-Myc and Ki67 expression in the SOX17 knockdown group compared to controls.
