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. 2016 Oct 13;7(46):76108–76117. doi: 10.18632/oncotarget.12627

Figure 4. ZNF703 promotes CCA tumor growth and metastasis in vivo.

Figure 4

A. Photomicrographs of xenograft tumors in nude mice. Representative images of a mouse in each group are presented. Tumor volumes in ZNF703 inhibited mice were smaller than those of control mice, while the largest tumors grown in ZNF703 overexpressed mice. B. Tumors from different groups were collected for western blot and immunohistochemical analysis in which ki-67 were counted to calculate the proliferation index. Pictures are representative of three independent experiments. C, D. The number of tumor masses formed in peritoneal cavity and lungs by QBC939 cells in the ZNF703 inhibited group were much smaller than those formed in control group and overexpressed group, respectively. The results are expressed as the mean ± SD of three independent experiments, *P <0.05.